Article
Association between a T/C polymorphism in intron 2 of cholesterol 24S-hydroxylase gene and Alzheimer's disease in Chinese.
Neuroscience letters - 14 Oct 2004
Wang Binbin, Zhang Chuanfang, Zheng Weidong, Lu Zeping, Zheng Chenguang, Yang Ze, Wang Li, Jin Feng
Abstract excerpt
A polymorphism (T/C) in intron 2 of the cholesterol 24-hydroxylase (CYP46) gene has recently been reported to be associated with the risk for late-onset Alzheimer's disease (LOAD). To investigate possible involvement of the CYP46 gene and apolipoprotein E (APOE) gene polymorphisms in the manifestation of LOAD, we analyzed 99 sporadic LOAD patients and 113 healthy controls of China. We found an obvious association...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
