Intron 2 (T/C) CYP46 polymorphism is associated with Alzheimer's disease in Chinese patients.

doi:10.1159/000095723

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Intron 2 (T/C) CYP46 polymorphism is associated with Alzheimer's disease in Chinese patients.

Dementia and geriatric cognitive disorders - 1 Jan 2006

Li Y, Chu L W, Chen Y Q, Cheung B M Y, Leung R Y H, Yik P Y, Ng K M, Mak W, Jin D Y, St George-Hyslop P, Song Y Q

Abstract excerpt

BACKGROUND: Cholesterol metabolism has been implicated in the pathophysiology of Alzheimer's disease (AD), and cholesterol-related genes are plausible candidate genes for AD. Genetic association of CYP46A1 polymorphisms with AD had been under extensive investigations; however, observations on intron 2 T-->C (rs754203) generated inconclusive results. OBJECTIVE: To analyse an independent data set in a Chinese...

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PMID: 16960449
DOI: 10.1159/000095723

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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