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Article

Spontaneous and induced chromosomal damage and mutations in Bloom Syndrome mice.

Mutation research - 4 Oct 2004

Wang Yanping, Heddle John A

Abstract excerpt

Bloom Syndrome (BS) is characterized by both cancer and genomic instability, including chromosomal aberrations, sister chromosome exchanges, and mutations. Since BS heterozygotes are much more frequent than homozygotes, the issue of the sensitivity of heterozygotes to cancer is an important one. This and many other questions concerning the effects of BLM (the gene responsible for the BS) are more easily studied...

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Source

Identifiers

PMID: 15450411
DOI: 10.1016/j.mrfmmm.2004.04.004

Genes

BLM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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