Article
A Genome-Wide Association Study for Regulators of Micronucleus Formation in Mice.
G3 (Bethesda, Md.) - 9 Aug 2016
McIntyre Rebecca E, Nicod Jérôme, Robles-Espinoza Carla Daniela, Maciejowski John, Cai Na, Hill Jennifer, Verstraten Ruth, Iyer Vivek, Rust Alistair G, Balmus Gabriel, Mott Richard, Flint Jonathan, Adams David J
Abstract excerpt
In mammals the regulation of genomic instability plays a key role in tumor suppression and also controls genome plasticity, which is important for recombination during the processes of immunity and meiosis. Most studies to identify regulators of genomic instability have been performed in cells in culture or in systems that report on gross rearrangements of the genome, yet subtle differences in the level of...
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