Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphisms of the RGS4 and dorsolateral prefrontal cortex morphometry among first episode schizophrenia patients.

Molecular psychiatry - 1 Feb 2005

Prasad K M R, Chowdari K V, Nimgaonkar V L, Talkowski M E, Lewis D A, Keshavan M S

Abstract excerpt

Polymorphisms of the gene encoding the regulator of G-protein signaling subtype 4 (RGS4) may confer risk for schizophrenia.(1) DNA microarray studies of postmortem brain samples have shown RGS4 underexpression in the dorsolateral prefrontal cortex (DLPFC, area 9), motor and visual cortices in schizophrenia patients relative to control subjects.(2) Underexpression of RGS4 in DLPFC is pathophysiologically...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to RGS4 gene
Share to Oligonucleotide Array Sequence Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Organ Size

Share to Polymorphism, Single Nucleotide

Share to Prefrontal Cortex

Share to Reference Values

Share to RGS Proteins

Share to Schizophrenia

Source

Identifiers

PMID: 15381923
DOI: 10.1038/sj.mp.4001562

Genes

RGS4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphisms of the RGS4 and dorsolateral prefrontal cortex morphometry among first episode schizophrenia patients.PMID 15381923Read ↗

RGS4 polymorphisms associated with variability of cognitive performance in a family-based schizophrenia sample.Semantic proximity Read ↗

Expression of RGS4 splice variants in dorsolateral prefrontal cortex of schizophrenic and bipolar disorder patients.Semantic proximity Read ↗

RGS4 mRNA expression in postmortem human cortex is associated with COMT Val158Met genotype and COMT enzyme activity.Semantic proximity Read ↗

Association of RGS2 and RGS5 variants with schizophrenia symptom severity.Semantic proximity Read ↗

Ethnic stratification of the association of RGS4 variants with antipsychotic treatment response in schizophrenia.Semantic proximity Read ↗

Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia.Semantic proximity Read ↗

Allelic variation in RGS4 impacts functional and structural connectivity in the human brain.Semantic proximity Read ↗

An association study of RGS4 polymorphisms with clinical phenotypes of schizophrenia in a Chinese population.Semantic proximity Read ↗

The Disrupted-in-Schizophrenia-1 Ser704Cys polymorphism and brain morphology in schizophrenia.Semantic proximity Read ↗

The impact of genome-wide supported schizophrenia risk variants in the neurogranin gene on brain structure and function.Semantic proximity Read ↗

Regulator of G-protein signalling 4 expression is not altered in the prefrontal cortex in schizophrenia.Semantic proximity Read ↗

Neuregulin-1 (NRG1) polymorphisms linked with psychosis transition are associated with enlarged lateral ventricles and white matter disruption in schizophrenia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.