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Article

Association of RGS2 and RGS5 variants with schizophrenia symptom severity.

Schizophrenia research - 1 Apr 2008

Campbell Daniel B, Lange Leslie A, Skelly Tara, Lieberman Jeffrey, Levitt Pat, Sullivan Patrick F

Abstract excerpt

BACKGROUND: Several lines of evidence indicate that Regulator of G Protein Signaling 4 (RGS4) contributes to schizophrenia vulnerability. RGS4 is one of a family of molecules that modulate signaling via G-protein coupled receptors. Five genes encoding members of this family (RGS2, RGS4, RGS5, RGS8 and RGS16) map to chromosome 1q23.3-1q31. Due to overlapping cellular functions and chromosomal proximity, we...

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Source

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Identifiers

PMID: 18262772
DOI: 10.1016/j.schres.2008.01.006
PMCID: PMC2486404

Genes

RGS2
RGS5
RGS4
RGS16
RGS8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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