Article
Regulator of G-protein signalling 4 expression is not altered in the prefrontal cortex in schizophrenia.
The Australian and New Zealand journal of psychiatry - 1 Aug 2008
Stuart Gibbons Andrew, Scarr Elizabeth, McOmish Caitlin E, Hannan Anthony J, Thomas Elizabeth A, Dean Brian
Abstract excerpt
OBJECTIVES: Regulator of G-protein signalling 4 (RGS4) modulates signal transduction through several neurotransmitter receptor systems associated with the pathology of schizophrenia. A reported decrease in RGS4 expression in the prefrontal cortex of schizophrenia patients followed by supporting evidence from association studies implicated RGS4 as a susceptibility gene for schizophrenia. Subsequent efforts to...
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