Article
RGS4 polymorphisms associated with variability of cognitive performance in a family-based schizophrenia sample.
Schizophrenia bulletin - 1 Sept 2010
Prasad Konasale M, Almasy Laura, Gur Ruben C, Gur Raquel E, Pogue-Geile Michael, Chowdari Kodavali V, Talkowski Michael E, Nimgaonkar Vishwajit L
Abstract excerpt
Polymorphisms of the gene encoding the regulator of G protein signaling, subtype 4 (RGS4), may be associated with schizophrenia. Among first-episode schizophrenia patients, they are also associated with dorsolateral prefrontal cortex (DLPFC) volume. The DLPFC is a key region that regulates heritable cognitive functions implicated in schizophrenia pathogenesis. To further understand the relationship of RGS4...
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