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Article

The Disrupted-in-Schizophrenia-1 Ser704Cys polymorphism and brain morphology in schizophrenia.

Psychiatry research - 15 May 2009

Takahashi Tsutomu, Suzuki Michio, Tsunoda Masahiko, Maeno Nobuhisa, Kawasaki Yasuhiro, Zhou Shi-Yu, Hagino Hirofumi, Niu Lisha, Tsuneki Hiroshi, Kobayashi Soushi, Sasaoka Toshiyasu, Seto Hikaru, Kurachi Masayoshi, Ozaki Norio

Abstract excerpt

The Disrupted-in-Schizophrenia-1 (DISC1) polymorphism is a strong candidate for a schizophrenia-susceptibility gene as it is widely expressed in cortical and limbic regions, but the effect of its genotype variation on brain morphology in schizophrenia is not well known. This study examined the association between the DISC1 Ser704Cys polymorphism and volumetric measurements for a broad range of fronto-parietal,...

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Source

Identifiers

PMID: 19304459
DOI: 10.1016/j.pscychresns.2009.01.005

Genes

DISC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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