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Article

An xrcc4 defect or Wortmannin stimulates homologous recombination specifically induced by double-strand breaks in mammalian cells.

Nucleic acids research - 1 Aug 2002

Delacôte Fabien, Han Mingguang, Stamato Thomas D, Jasin Maria, Lopez Bernard S

Abstract excerpt

Non-homologous end joining (NHEJ) and homologous recombination (HR) are two alternative/competitor pathways for the repair of DNA double-strand breaks (DSBs). To gain further insights into the regulation of DSB repair, we detail here the different HR pathways affected by (i) the inactivation of D...

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PMID: 12140331
DOI: 10.1093/nar/gkf452
PMCID: PMC137076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12140331-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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