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Article

Expression of adenomatous polyposis coli (APC) in tumorigenesis of human oral squamous cell carcinoma.

Oral oncology - 1 Oct 2004

Tsuchiya Reiko, Yamamoto Gou, Nagoshi Yuuki, Aida Tadateru, Irie Tarou, Tachikawa Tetsuhiko

Abstract excerpt

The product of the adenomatous polyposis coli (APC) tumor suppressor gene has been observed to regulate the Wnt signaling pathway through beta-catenin. In the present study, we attempted to clarify the relation between APC and the canceration of oral squamous epithelium. Each target tissue of normal squamous epithelium, epithelial dysplasia, and squamous cell carcinoma (SCC) was recovered the oral SCC case by...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carcinoma, Squamous Cell

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Source

Identifiers

PMID: 15380172
DOI: 10.1016/j.oraloncology.2004.04.011

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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