Article
Abnormalities of the adenomatous polyposis coli gene in human oral squamous-cell carcinoma.
International journal of cancer - 15 Sept 1994
Uzawa K, Yoshida H, Suzuki H, Tanzawa H, Shimazaki J, Seino S, Sato K
Abstract excerpt
Recent studies have suggested that abnormalities in the adenomatous polyposis coli gene (APC gene) are associated with the development not only of familial adenomatous polyposis coli (FAP) but also of cancers in digestive organs. In order to elucidate whether abnormalities of the APC gene could c...
Topics
- Base Sequence
- Carcinoma, Squamous Cell
- DNA, Neoplasm
- DNA, Single-Stranded
- Exons
- Gene Deletion
- Genes, APC
- Heterozygote
- Humans
- Molecular Sequence Data
- Mouth Neoplasms
- Mutation
- Nucleic Acid Conformation
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Reference Values
- Sequence Analysis, DNA