Article
Adenomatous polyposis coli gene mutation and decreased wild-type p53 protein expression in oral submucous fibrosis: a preliminary investigation.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics - 1 Aug 2001
Liao P H, Lee T L, Yang L C, Yang S H, Chen S L, Chou M Y
Abstract excerpt
OBJECTIVE: The purpose of this study was to identify the adenomatous polyposis coli (APC) tumor suppressor gene mutation and level of wild-type p53 protein expression in patients with oral submucous fibrosis (OSF). STUDY DESIGN: Cells from OSF and control subjects were cultured in Dulbecco modified Eagle medium with 10% fetal bovine serum at 37 degrees C. Genomic DNA was extracted from cultured cells and used as...
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