Article
Mutations of the adenomatous polyposis coli gene in areca quid and tobacco-associated oral squamous cell carcinomas in Taiwan.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Aug 2002
Kok Sang-Heng, Lee Jang-Jaer, Hsu Hey-Chi, Chiang Chun-Pin, Kuo Ying-Shiung, Kuo Mark Yen-Ping
Abstract excerpt
BACKGROUND: Adenomatous polyposis coli (APC) gene mutations have been demonstrated not only in colorectal tumors but also in a variety of human cancers. METHODS: To elucidate the possible roles of APC gene mutations in oral squamous cell carcinomas (OSCCs), we examined 40 untreated human primary OSCCs using polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) and DNA sequencing assays....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.