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Article

A proinflammatory role for Fas in joints of mice with collagen-induced arthritis.

Arthritis research & therapy - 1 Jan 2004

Tu-Rapp Hoang, Hammermüller André, Mix Eilhard, Kreutzer Hans-Jürgen, Goerlich Roland, Köhler Hansjürgen, Nizze Horst, Thiesen Hans-Jürgen, Ibrahim Saleh M

Abstract excerpt

Collagen-induced arthritis (CIA) is a chronic inflammatory disease bearing all the hallmarks of rheumatoid arthritis, e.g. polyarthritis, synovitis, and subsequent cartilage/bone erosions. One feature of the disease contributing to joint damage is synovial hyperplasia. The factors responsible for the hyperplasia are unknown; however, an imbalance between rates of cell proliferation and cell death (apoptosis) has...

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Identifiers

PMID: 15380040
DOI: 10.1186/ar1205
PMCID: PMC546278

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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