Article
A non-major histocompatibility locus determines tissue specificity in the pathogenic process underlying synovial proliferation in a mouse arthropathy model.
Annals of the rheumatic diseases - 1 Feb 2007
Zhang Ming-Cai, Mori Shiro, Date Fumiko, Furukawa Hiroshi, Ono Masao
Abstract excerpt
BACKGROUND: The incidence and characteristics of spontaneous ankylosis in the ankle of specific F(1) mice descended from two Fas-deficient strains were reported. Here the coincidence of synovial proliferation and ankylosis in the descendent F(2) mice is reported. AIM: To clarify whether the two distinct manifestations are genetically different. METHODS: An arthropathic group of mice (MCF(2)) were bred by...
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