Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Osteoclast Apoptosis: The Role of Fas<i>in Vivo</i>and<i>in Vitro</i>

26 Aug 2003

Abstract excerpt

Both the number and the activity of osteoclasts are critical for maintaining normal bone turnover. The number is determined by rates of cell differentiation and death. Fas-mediated apoptosis is a dominant mechanism for apoptosis. Here, we show the presence of the Fas receptor on mouse, human, avian, and cultured RAW264.7 (murine) derived osteoclasts and the up-regulation of its expression during mouse osteoclast...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone health and treatments
Share to Bone Metabolism and Diseases
Share to Cell death mechanisms and regulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12960091
DOI: 10.1210/en.2003-0296

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Osteoclast Apoptosis: The Role of Fas<i>in Vivo</i>and<i>in Vitro</i>PMID 12960091Read ↗

Major vault protein (MVP) suppresses aging- and estrogen deficiency-related bone loss through Fas-mediated apoptosis in osteoclastsSemantic proximity Read ↗

Estrogen prevents bone loss via estrogen receptor alpha and induction of Fas ligand in osteoclasts.Semantic proximity Read ↗

Fas Ligand-Induced ApoptosisSemantic proximity Read ↗

The central role of Fas‐ligand cell signaling in inflammatory lung diseasesSemantic proximity Read ↗

Apoptosis regulated by a death factor and its receptor: Fas ligand and Fas.Semantic proximity Read ↗

Regulatory roles and molecular signaling of TNF family members in osteoclastsSemantic proximity Read ↗

Apoptosis in bone physiology and disease.Semantic proximity Read ↗

The antiapoptotic protein Bcl-xL negatively regulates the bone-resorbing activity of osteoclasts in miceSemantic proximity Read ↗

The Programmed Death-1 Pathway Counter-Regulates Inflammation-Induced Osteoclast Activity in Clinical and Experimental SettingsSemantic proximity Read ↗

Recent Advances in Osteoclast Biological BehaviorSemantic proximity Read ↗

Increased bone mass is a part of the generalized lymphoproliferative disorder phenotype in the mouse.Semantic proximity Read ↗

Apoptosis during bone-like tissue development in vitro.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.