Fas ligand deficiency impairs host inflammatory response against infection with the spirochete Borrelia burgdorferi.

Abstract excerpt

Lyme disease represents a complex response to Borrelia burgdorferi that involves both bacterial factors as well as host responses. This results in an inflammatory reaction at several sites, including the synovial lining of joints. Synovial tissues of inflamed joints contain cells expressing high levels of Fas and Fas ligand (FasL). Although Fas stimulation is typically associated with cell death, it can also...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Mice, Congenic
• Share to Antibodies, Bacterial