Article
A role for the Fanconi anemia C protein in maintaining the DNA damage-induced G2 checkpoint.
The Journal of biological chemistry - 3 Dec 2004
Freie Brian W, Ciccone Samantha L M, Li Xiaxin, Plett P Artur, Orschell Christie M, Srour Edward F, Hanenberg Helmut, Schindler Detlev, Lee Suk-Hee, Clapp D Wade
Abstract excerpt
Fanconi anemia (FA) is a complex, heterogeneous genetic disorder composed of at least 11 complementation groups. The FA proteins have recently been found to functionally interact with the cell cycle regulatory proteins ATM and BRCA1; however, the function of the FA proteins in cell cycle control remains incompletely understood. Here we show that the Fanconi anemia complementation group C protein (Fancc) is...
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