Article
The Caenorhabditis elegans kinetochore reorganizes at prometaphase and in response to checkpoint stimuli.
Molecular biology of the cell - 1 Nov 2004
Stear Jeffrey H, Roth Mark B
Abstract excerpt
Previous studies of the kinetochore in mammalian systems have demonstrated that this structure undergoes reorganizations after microtubule attachment or in response to activation of the spindle checkpoint. Here, we show that the Caenorhabditis elegans kinetochore displays analogous rearrangements at prometaphase, when microtubule/chromosome interactions are being established, and after exposure to checkpoint...
Topics
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cell Cycle
- Cell Cycle Proteins
- Centromere
- Chromosomal Proteins, Non-Histone
- Histones
- Hypoxia
- Kinetochores
- Metaphase