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Article

Metaphase to anaphase (mat) transition-defective mutants in Caenorhabditis elegans.

The Journal of cell biology - 25 Dec 2000

Golden A, Sadler P L, Wallenfang M R, Schumacher J M, Hamill D R, Bates G, Bowerman B, Seydoux G, Shakes D C

Abstract excerpt

The metaphase to anaphase transition is a critical stage of the eukaryotic cell cycle, and, thus, it is highly regulated. Errors during this transition can lead to chromosome segregation defects and death of the organism. In genetic screens for temperature-sensitive maternal effect embryonic lethal (Mel) mutants, we have identified 32 mutants in the nematode Caenorhabditis elegans in which fertilized embryos...

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Identifiers

PMID: 11134076
DOI: 10.1083/jcb.151.7.1469
PMCID: PMC2150685

Genes

CDC16

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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