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Article

Mislocalization of the Drosophila centromere-specific histone CID promotes formation of functional ectopic kinetochores.

Developmental cell - 1 Mar 2006

Heun Patrick, Erhardt Sylvia, Blower Michael D, Weiss Samara, Skora Andrew D, Karpen Gary H

Abstract excerpt

The centromere-specific histone variant CENP-A (CID in Drosophila) is a structural and functional foundation for kinetochore formation and chromosome segregation. Here, we show that overexpressed CID is mislocalized into normally noncentromeric regions in Drosophila tissue culture cells and animals. Analysis of mitoses in living and fixed cells reveals that mitotic delays, anaphase bridges, chromosome...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16516834
DOI: 10.1016/j.devcel.2006.01.014
PMCID: PMC3192491

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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