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Article

Specific requirements of sonic hedgehog signaling during oligodendrocyte development.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Nov 2005

Oh Saeock, Huang Xi, Chiang Chin

Abstract excerpt

Oligodendrocyte precursors (OLPs) in the developing spinal cord are generated from the same part of the ventral neuroepithelium as motor neurons, by inductive processes that include a temporal switch from neuronal to glial cell fate. Recent studies have implicated Shh as a key signal in the generation of both OLPs and ventral neurons. In this study, we used Shh(-/-), Gli3(-/-), and Shh(-/-);Gli3(-/-) mutants to...

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Identifiers

PMID: 15880651
DOI: 10.1002/dvdy.20422

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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