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Article

Sonic hedgehog contributes to oligodendrocyte specification in the mammalian forebrain.

Development (Cambridge, England) - 1 Feb 2001

Nery S, Wichterle H, Fishell G

Abstract excerpt

This study addresses the role of Sonic hedgehog (Shh) in promoting the generation of oligodendrocytes in the mouse telencephalon. We show that in the forebrain, expression of the early oligodendrocyte markers Olig2, plp/dm20 and PDGFR(alpha) corresponds to regions of Shh expression. To directly test if Shh can induce the development of oligodendrocytes within the telencephalon, we use retroviral vectors to...

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Source

Identifiers

PMID: 11171336
DOI: 10.1242/dev.128.4.527

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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