Article
Improved PC1/3 production through recombinant expression in insect cells and larvae.
Protein expression and purification - 1 Oct 2004
Rabah Nadia, Gauthier Daniel J, Gauthier Dany, Lazure Claude
Abstract excerpt
Protein convertase 1/3 is a serine endoproteinase present in the regulated secretory pathway of endocrine and neuroendocrine cells. It is responsible for the processing of numerous prohormones and proneuropeptides into their biologically active moieties, often following cleavage at pairs of basic residues. The determination of its three-dimensional structure, as well as the understanding of its enzymatic...
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