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Article

Involvement of a polyproline helix-like structure in the interaction of 7B2 with prohormone convertase 2.

The Journal of biological chemistry - 20 Sept 1996

Zhu X, Lamango N S, Lindberg I

Abstract excerpt

The neuroendocrine protein 7B2 is known to be involved in the biosynthesis and activity of prohormone convertase 2 (PC2). Previous studies have demonstrated that while the carboxyl-terminal portion of 7B2 (residues 155-186) regulates the enzymatic activity of PC2, the amino terminus of the molecule (residues 1-151) is required for maturation of proPC2. In this study we employed four different experimental...

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Identifiers

PMID: 8798569
DOI: 10.1074/jbc.271.38.23582

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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