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Article

Expression, purification and characterization of enterovirus-71 virus-like particles

1 Jan 2006

Abstract excerpt

AIM: Enterovirus 71 (EV71) has been implicated as the etiological agent responsible for the recent outbreaks of hand, foot and mouth disease associated with severe neurological diseases in the Asia-Pacific region. METHODS: The assembly process was hypothesized to occur via an orchestrated proteolytic processing of the P1 precursor by the viral protease 3CD. To test this hypothesis, we constructed 3 recombinant...

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PMID: 16521221
DOI: 10.3748/wjg.v12.i6.921

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