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Article

Purification of Recombinant Human Tyrosinase from Insect Larvae Infected with the Baculovirus Vector.

Current protocols in protein science - 1 Aug 2017

Dolinska Monika B, Wingfield Paul T, Sergeev Yuri V

Abstract excerpt

The purification of an enzyme from insect larvae infected with a baculovirus vector is described. The enzyme tyrosinase is of biomedical importance and catalyzes the first rate-limiting steps in melanin production. Tyrosinase mutations can result in oculocutaneous albinism type 1 (OCA1), an inherited eye disease associated with decreased melanin pigment production and vision defects. To simplify expression and...

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Identifiers

PMID: 28762492
DOI: 10.1002/cpps.37
PMCID: PMC5653277

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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