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Article

Susceptibility to neoplastic and non-neoplastic pulmonary diseases in mice: genetic similarities.

American journal of physiology. Lung cellular and molecular physiology - 1 Oct 2004

Bauer Alison K, Malkinson Alvin M, Kleeberger Steven R

Abstract excerpt

Chronic inflammation predisposes toward many types of cancer. Chronic bronchitis and asthma, for example, heighten the risk of lung cancer. Exactly which inflammatory mediators (e.g., oxidant species and growth factors) and lung wound repair processes (e.g., proangiogenic factors) enhance pulmonary neoplastic development is not clear. One approach to uncover the most relevant biochemical and physiological...

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Identifiers

PMID: 15355860
DOI: 10.1152/ajplung.00223.2003

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