Article
Genetic predisposition to chronic obstructive pulmonary disease and/or lung cancer: important considerations when evaluating risk.
Cancer prevention research (Philadelphia, Pa.) - 1 Apr 2012
El-Zein Randa A, Young Robert P, Hopkins Raewyn J, Etzel Carol J
Abstract excerpt
Chronic obstructive pulmonary disease (COPD) is defined as a disease causing an airflow limitation that is not fully reversible. COPD is phenotypically complex and characterized by small-airway disease and/or emphysema that result from the interaction between host genetic susceptibility and envir...
Topics
- Adult
- Aged
- Aged, 80 and over
- Female
- Genetic Predisposition to Disease
- Genetic Variation
- Genome-Wide Association Study
- Humans
- Lung Neoplasms
- Male
- Middle Aged
- Models, Genetic
- Phenotype
- Prevalence
- Pulmonary Disease, Chronic Obstructive
- Risk
- Risk Factors
- Smoking