Article
Genetic predisposition to chronic obstructive pulmonary disease and/or lung cancer: important considerations when evaluating risk.
Cancer prevention research (Philadelphia, Pa.) - 1 Apr 2012
El-Zein Randa A, Young Robert P, Hopkins Raewyn J, Etzel Carol J
Abstract excerpt
Chronic obstructive pulmonary disease (COPD) is defined as a disease causing an airflow limitation that is not fully reversible. COPD is phenotypically complex and characterized by small-airway disease and/or emphysema that result from the interaction between host genetic susceptibility and environmental exposures. As in lung cancer, smoking exposure is the most important risk factor for the development of COPD,...
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