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Article

Phospholipase Cepsilon regulates ovulation in Caenorhabditis elegans.

Developmental biology - 1 Oct 2004

Kariya Ken-Ichi, Bui Yen Kim, Gao Xianlong, Sternberg Paul W, Kataoka Tohru

Abstract excerpt

Phospholipase Cepsilon (PLCepsilon) is a novel class of phosphoinositide-specific PLC with unknown physiological functions. Here, we present the first genetic analysis of PLCepsilon in an intact organism, the nematode Caenorhabditis elegans. Ovulation in C. elegans is dependent on an inositol 1,4,5-trisphosphate (IP(3)) signaling pathway activated by the receptor tyrosine kinase LET-23. We generated deletion...

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PMID: 15355798
DOI: 10.1016/j.ydbio.2004.06.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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