Article
Inositol 1,4,5-trisphosphate signaling regulates mating behavior in Caenorhabditis elegans males.
Molecular biology of the cell - 1 Sept 2005
Gower Nicholas J D, Walker Denise S, Baylis Howard A
Abstract excerpt
Complex behavior requires the coordinated action of the nervous system and nonneuronal targets. Male mating in Caenorhabditis elegans consists of a series of defined behavioral steps that lead to the physiological outcomes required for successful impregnation. We demonstrate that signaling mediated by inositol 1,4,5-trisphosphate (IP(3)) is required at several points during mating. Disruption of IP(3) receptor...
Topics
- Animals
- Antinematodal Agents
- Caenorhabditis elegans
- Calcium Channels
- Calcium Signaling
- Fertility
- Inositol 1,4,5-Trisphosphate
- Inositol 1,4,5-Trisphosphate Receptors
- Isoenzymes
- Levamisole
- Male
- Mutation
- Phospholipase C beta
- RNA Interference