Article
PAR-3 is required for epithelial cell polarity in the distal spermatheca of C. elegans.
Development (Cambridge, England) - 1 Jun 2004
Aono Shinya, Legouis Renaud, Hoose Wendy A, Kemphues Kenneth J
Abstract excerpt
PAR-3 is localized asymmetrically in epithelial cells in a variety of animals from Caenorhabditis elegans to mammals. Although C. elegans PAR-3 is known to act in early blastomeres to polarize the embryo, a role for PAR-3 in epithelial cells of C. elegans has not been established. Using RNA interference to deplete PAR-3 in developing larvae, we discovered a requirement for PAR-3 in spermathecal development....
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