Article
DPL-1 (DP) acts in the germ line to coordinate ovulation and fertilization in C. elegans.
Mechanisms of development - 1 Jan 2000
Chi Woo, Reinke Valerie
Abstract excerpt
Proper coordination of oogenesis, ovulation, and fertilization is essential for successful reproduction. In Caenorhabditis elegans, a strong loss-of-function mutation in dpl-1, which encodes a subunit of the E2F heterodimeric transcription factor EFL-1/DPL-1, causes severe defects during ovulation and fertilization. Here we demonstrate that the somatic gonad structure and sheath cell contraction rate appear...
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