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Article

APC dosage effects in tumorigenesis and stem cell differentiation.

The International journal of developmental biology - 1 Jan 2004

Gaspar Claudia, Fodde Riccardo

Abstract excerpt

It is well established that concentration gradients of signaling molecules (the so-called "morphogens") organize and pattern tissues in developing animals. In particular, studies in Drosophila and different vertebrates have shown that gradients of the Wnt, Hedgehog (Hh) and transforming growth factor-beta (TGF-beta) families of morphogens play critical roles in limb patterning. Morphogens are often expressed in...

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Source

Identifiers

PMID: 15349813
DOI: 10.1387/ijdb.041807cg

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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