Article
Autonomous and nonautonomous regulation of axis formation by antagonistic signaling via 7-span cAMP receptors and GSK3 in Dictyostelium.
Genes & development - 15 Aug 1997
Ginsburg G T, Kimmel A R
Abstract excerpt
Early during Dictyostelium development a fundamental cell-fate decision establishes the anteroposterior (prestalk/prespore) axis. Signaling via the 7-transmembrane cAMP receptor CAR4 is essential for creating and maintaining a normal pattern; car4-null alleles have decreased levels of prestalk-sp...
Topics
- Animals
- Caenorhabditis elegans Proteins
- Calcium-Calmodulin-Dependent Protein Kinases
- Carrier Proteins
- Cell Differentiation
- Cyclic AMP
- DNA Probes
- Dictyostelium
- Drosophila
- Gene Expression Regulation, Developmental
- Glycogen Synthase Kinase 3
- Helminth Proteins
- Hexanones
- Hydrocarbons, Chlorinated
- Mutation
- Proteins
- Protozoan Proteins
- Receptors, Cyclic AMP