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Article

Autonomous and nonautonomous regulation of axis formation by antagonistic signaling via 7-span cAMP receptors and GSK3 in Dictyostelium.

Genes & development - 15 Aug 1997

Ginsburg G T, Kimmel A R

Abstract excerpt

Early during Dictyostelium development a fundamental cell-fate decision establishes the anteroposterior (prestalk/prespore) axis. Signaling via the 7-transmembrane cAMP receptor CAR4 is essential for creating and maintaining a normal pattern; car4-null alleles have decreased levels of prestalk-specific mRNAs but enhanced expression of prespore genes. car4- cells produce all of the signals required for prestalk...

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Identifiers

PMID: 9284050
DOI: 10.1101/gad.11.16.2112
PMCID: PMC316452

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