Article
Glycogen synthase kinase-3 (GSK-3) is regulated during Dictyostelium development via the serpentine receptor cAR3.
Development (Cambridge, England) - 1 Jan 1999
Plyte S E, O'Donovan E, Woodgett J R, Harwood A J
Abstract excerpt
Glycogen synthase kinase-3 (GSK-3) is required during metazoan development to mediate the effects of the extracellular signal wingless/Wnt-1 and hence is necessary for correct cell type specification. GSK-3 also regulates cell fate during Dictyostelium development, but in this case it appears to...
Topics
- Amino Acid Sequence
- Animals
- Calcium-Calmodulin-Dependent Protein Kinases
- Cell Differentiation
- Cyclic AMP
- Dictyostelium
- Gene Expression Regulation, Developmental
- Glycogen Synthase Kinase 3
- Glycogen Synthase Kinases
- Lac Operon
- Molecular Sequence Data
- Mutation
- Receptors, Cyclic AMP
- Signal Transduction
- Transformation, Genetic