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Article

Trishanku, a novel regulator of cell-type stability and morphogenesis in Dictyostelium discoideum.

Differentiation; research in biological diversity - 1 Dec 2006

Jaiswal Jyoti K, Mujumdar Nameeta, Macwilliams Harry K, Nanjundiah Vidyanand

Abstract excerpt

We have identified a novel gene, trishanku (triA), by random insertional mutagenesis of Dictyostelium discoideum. TriA is a Broad complex Tramtrack bric-a-brac domain-containing protein that is expressed strongly during the late G2 phase of cell cycle and in presumptive spore (prespore (psp)) cells. Disrupting triA destabilizes cell fate and reduces aggregate size; the fruiting body has a thick stalk, a lowered...

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PMID: 17177856
DOI: 10.1111/j.1432-0436.2006.00086.x

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