Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification and characterization of single-nucleotide polymorphisms in MCH-R1 and MCH-R2.

Obesity research - 1 Aug 2004

Hawes Brian E, Green Beverly, O'Neill Kim, Fried Steve, Arreaza M Gladys, Qiu Ping, Simon Jason S

Abstract excerpt

OBJECTIVE: To identify and functionally characterize single-nucleotide polymorphisms (SNPs) in melanin-concentrating hormone (MCH)-R1 and -R2. RESEARCH METHODS AND PROCEDURES: The entire coding regions and intron/exon splice junction regions of MCH-R1 and MCH-R2 were sequenced from anonymous white (n=45) and African-American (n=46) individuals. DNA was analyzed, and SNPs were identified using Phred, Phrap, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Black or African American
Share to Black People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Introns

Share to Melanins

Share to Pituitary Hormones

Share to Receptors, G-Protein-Coupled

Share to Receptors, Somatostatin

Share to RNA Splicing

Source

Identifiers

PMID: 15340116
DOI: 10.1038/oby.2004.167

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification and characterization of single-nucleotide polymorphisms in MCH-R1 and MCH-R2.PMID 15340116Read ↗

Melanin-concentrating hormone receptor mutations and human obesity: functional analysis.Semantic proximity Read ↗

Two naturally occurring mutations in the type 1 melanin-concentrating hormone receptor abolish agonist-induced signaling.Semantic proximity Read ↗

Mutation analysis of the MCHR1 gene in human obesity.Semantic proximity Read ↗

Identification and pharmacological analyses of eight naturally occurring caprine melanocortin-1 receptor mutations in three different goat breeds.Semantic proximity Read ↗

Association of melanin-concentrating hormone receptor 1 5' polymorphism with early-onset extreme obesity.Semantic proximity Read ↗

Single nucleotide polymorphisms of the MCHR1 gene do not affect metabolism in humans.Semantic proximity Read ↗

Structure and expression of the variant melanin-concentrating hormone genes: only PMCHL1 is transcribed in the developing human brain and encodes a putative protein.Semantic proximity Read ↗

Isolation and characterization of the human melanin-concentrating hormone gene and a variant gene.Semantic proximity Read ↗

Genetic study of the melanin-concentrating hormone receptor 2 in childhood and adulthood severe obesity.Semantic proximity Read ↗

Selected melanocortin 1 receptor single-nucleotide polymorphisms differentially alter multiple signaling pathways.Semantic proximity Read ↗

Obesity-associated MRAP2 variants impair multiple MC4R-mediated signaling pathwaysSemantic proximity Read ↗

Pharmacologic analyses of four chicken melanocortin-4 receptor mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.