Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic study of the melanin-concentrating hormone receptor 2 in childhood and adulthood severe obesity.

The Journal of clinical endocrinology and metabolism - 1 Nov 2007

Ghoussaini Maya, Vatin Vincent, Lecoeur Cécile, Abkevich Victor, Younus Adib, Samson Chantal, Wachter Christophe, Heude Barbara, Tauber Maïté, Tounian Patrick, Hercberg Serge, Weill Jacques, Levy-Marchal Claire, Le Stunff Catherine, Bougnères Pierre, Froguel Philippe, Meyre David

Abstract excerpt

CONTEXT: The melanin-concentrating hormone receptor 2 (MCHR2) is a G protein-coupled receptor for melanin-concentrating hormone, a neuropeptide that plays an important role in feeding behaviors. MCHR2 maps on chromosome 6q16.3, in a susceptibility locus for childhood obesity. OBJECTIVE: The aim of this study was to investigate the association between MCHR2 variation and human obesity. DESIGN: Case control and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Appetite
Share to Body Mass Index

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Replication

Share to Feeding and Eating Disorders

Share to Feeding Behavior

Share to Genetic Linkage

Share to Obesity

Share to Receptors, G-Protein-Coupled

Source

Identifiers

PMID: 17698913
DOI: 10.1210/jc.2006-2316

Genes

MCHR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic study of the melanin-concentrating hormone receptor 2 in childhood and adulthood severe obesity.PMID 17698913Read ↗

Melanin-concentrating hormone receptor mutations and human obesity: functional analysis.Semantic proximity Read ↗

Association of melanin-concentrating hormone receptor 1 5' polymorphism with early-onset extreme obesity.Semantic proximity Read ↗

Mutation analysis of the MCHR1 gene in human obesity.Semantic proximity Read ↗

Rare Variants in Genes Linked to Appetite Control and Hypothalamic Development in Early-Onset Severe Obesity.Semantic proximity Read ↗

Clinical and Functional Characterization of Melanocortin 4 Receptor genetic variants in African American and/or Hispanic children with severe early onset obesity.Semantic proximity Read ↗

Melanocortin 4 receptor mutations in a large cohort of severely obese adults: prevalence, functional classification, genotype-phenotype relationship, and lack of association with binge eating.Semantic proximity Read ↗

Characterization of Rare Variants in MC4R in African American and Latino Children With Severe Early-Onset Obesity.Semantic proximity Read ↗

Expression of Melanin-Concentrating Hormone Receptor 2 Protects Against Diet-Induced Obesity in Male MiceSemantic proximity Read ↗

Common genetic variation in and near the melanocortin 4 receptor gene (MC4R) is associated with body mass index in American Indian adults and children.Semantic proximity Read ↗

Evidence that multiple genetic variants of MC4R play a functional role in the regulation of energy expenditure and appetite in Hispanic children.Semantic proximity Read ↗

Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity.Semantic proximity Read ↗

The central melanocortin system and human obesity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.