Article
Pharmacologic analyses of four chicken melanocortin-4 receptor mutations.
Domestic animal endocrinology - 1 Jan 2016
Wang Z-Q, Huang J-S, Zhou J-H, Shi L, Jiang X-F, Tao Y-X
Abstract excerpt
The melanocortin-4 receptor (MC4R) is a critical regulator of mammalian food intake and energy expenditure, with receptor activation resulting in decreased food intake and increased energy expenditure. Recently, studies on role of MC4R in regulation of food intake have been extended to other species, such as chicken. Functional study of mutant MC4Rs is important in proving the causal link between MC4R mutation...
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