Article
Single nucleotide polymorphisms of the MCHR1 gene do not affect metabolism in humans.
Obesity (Silver Spring, Md.) - 1 Dec 2007
Rutanen Jarno, Pihlajamäki Jussi, Vänttinen Markku, Salmenniemi Urpu, Ruotsalainen Eija, Kuulasmaa Teemu, Kainulainen Sakari, Kuusisto Johanna, Laakso Markku
Abstract excerpt
Melanin concentrating hormone receptor-1 (MCHR1) is a centrally and peripherally expressed receptor that regulates energy expenditure and appetite. Single nucleotide polymorphisms (SNPs) of the MCHR1 gene have been previously associated with obesity, but the results are inconsistent among different populations. This study was performed to determine whether SNPs of MCHR1 affect glucose and energy metabolism. We...
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