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Article

Low-density lipoprotein particle size loci in familial combined hyperlipidemia: evidence for multiple loci from a genome scan.

Arteriosclerosis, thrombosis, and vascular biology - 1 Oct 2004

Badzioch Michael D, Igo Robert P, Gagnon France, Brunzell John D, Krauss Ronald M, Motulsky Arno G, Wijsman Ellen M, Jarvik Gail P

Abstract excerpt

OBJECTIVE: Low-density lipoprotein (LDL) size is associated with vascular disease and with familial combined hyperlipidemia (FCHL). METHODS AND RESULTS: We used logarithm of odds (lod) score and Bayesian Markov chain Monte Carlo (MCMC) linkage analysis methods to perform a 10-cM genome scan of LDL size, measured as peak particle diameter (PPD) and adjusted for age, sex, body mass index, and triglycerides in 4...

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Share to Genetic Linkage
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyperlipidemia, Familial Combined

Share to Lipoproteins, LDL

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Share to Multifactorial Inheritance

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Source

Identifiers

PMID: 15331429
DOI: 10.1161/01.ATV.0000143499.09575.93

Genes

CETP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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