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Article

Evidence for a major quantitative trait locus on chromosome 17q21 affecting low-density lipoprotein peak particle diameter.

Circulation - 13 May 2003

Bossé Yohan, Pérusse Louis, Després Jean-Pierre, Lamarche Benoît, Chagnon Yvon C, Rice Treva, Rao D C, Bouchard Claude, Vohl Marie-Claude

Abstract excerpt

BACKGROUND: Several lines of evidence suggest that small dense LDL particles are associated with the risk of coronary heart disease. Heritability and segregation studies suggest that LDL particle size is characterized by a large genetic contribution and the presence of a putative major genetic locus. However, association and linkage analyses have thus far been inconclusive in identifying the underlying gene(s)....

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Share to Chromosomes, Human, Pair 17
Share to Linkage Disequilibrium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipoproteins, LDL

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Source

Identifiers

PMID: 12732599
DOI: 10.1161/01.CIR.0000065577.60129.F5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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