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Article

Families with familial combined hyperlipidemia and families enriched for coronary artery disease share genetic determinants for the atherogenic lipoprotein phenotype.

American journal of human genetics - 1 Aug 1998

Allayee H, Aouizerat B E, Cantor R M, Dallinga-Thie G M, Krauss R M, Lanning C D, Rotter J I, Lusis A J, de Bruin T W

Abstract excerpt

Small, dense LDL particles consistently have been associated with hypertriglyceridemia, premature coronary artery disease (CAD), and familial combined hyperlipidemia (FCH). Previously, we have observed linkage of LDL particle size with four separate candidate-gene loci in a study of families enriched for CAD. These loci contain the genes for manganese superoxide dismutase (MnSOD), on chromosome 6q; for...

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Identifiers

PMID: 9683614
DOI: 10.1086/301983
PMCID: PMC1377323

Genes

CAD
CETP
LCAT
LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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