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Article

Multilocus genetic determinants of LDL particle size in coronary artery disease families.

American journal of human genetics - 1 Mar 1996

Rotter J I, Bu X, Cantor R M, Warden C H, Brown J, Gray R J, Blanche P J, Krauss R M, Lusis A J

Abstract excerpt

Recent interest in atherosclerosis has focused on the genetic determinants of low-density lipoprotein (LDL) particle size, because of (i) the association of small dense LDL particles with a three-fold increased risk for coronary artery disease (CAD) and (ii) the recent report of linkage of the trait to the LDL receptor (chromosome 19). By utilizing nonparametric quantitative sib-pair and relative-pair analysis...

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Identifiers

PMID: 8644718
PMCID: PMC1914567

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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