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Article

Investigation of LRP8 gene in 1p31 QTL linked to LDL peak particle diameter in the Quebec family study.

Molecular genetics and metabolism - 1 Apr 2011

Dolley G, Lamarche B, Després J P, Bouchard C, Pérusse L, Vohl M C

Abstract excerpt

The small, dense LDL phenotype is associated with an increased cardiovascular disease risk. A genome-wide scan performed on 236 nuclear families of the Quebec Family Study (QFS) revealed a quantitative trait locus affecting LDL peak particle diameter (LDL-PPD) and density on the 1p31 region. This region contains the low-density lipoprotein receptor-related protein 8 (LRP8) gene. LRP8, a receptor for...

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Share to Apolipoproteins B
Share to Cholesterol, LDL
Share to Chromosomes, Human, Pair 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lipid Metabolism

Share to Lipoproteins, HDL

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Source

Identifiers

PMID: 21316997
DOI: 10.1016/j.ymgme.2010.12.011

Genes

LRP8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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