Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantifiable cytotoxic T lymphocyte responses and HLA-related risk of progression to AIDS.

Proceedings of the National Academy of Sciences of the United States of America - 17 Aug 2004

Scherer Almut, Frater John, Oxenius Annette, Agudelo Juliet, Price David A, Günthard Huldrych F, Barnardo Martin, Perrin Luc, Hirschel Bernard, Phillips Rodney E, McLean Angela R

Abstract excerpt

There are significant associations between possession of certain HLA class I alleles and rate of progression to AIDS. Immunological data provide an explanatory mechanism for this relationship. Patients with HLA types associated with rapid disease progression recognize a significantly smaller fraction of their known repertoire of viral epitopes than do patients with HLA types associated with slow progression....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acquired Immunodeficiency Syndrome
Share to Genes, MHC Class I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA Antigens

Share to Longitudinal Studies

Share to Models, Immunological

Share to Switzerland

Share to T-Lymphocytes, Cytotoxic

Source

Open in PubMed Open full text

Identifiers

PMID: 15302942
DOI: 10.1073/pnas.0404091101
PMCID: PMC514467

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantifiable cytotoxic T lymphocyte responses and HLA-related risk of progression to AIDS.PMID 15302942Read ↗

HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1.Semantic proximity Read ↗

Advantage of rare HLA supertype in HIV disease progression.Semantic proximity Read ↗

New class I and II HLA alleles strongly associated with opposite patterns of progression to AIDS.Semantic proximity Read ↗

HLA alleles associated with slow progression to AIDS truly prefer to present HIV-1 p24.Semantic proximity Read ↗

HLA class I associations with rates of HIV-1 seroconversion and disease progression in the Pumwani Sex Worker Cohort.Semantic proximity Read ↗

Progression of HIV infection is associated with HLA-DQ antigens in Caucasians and African Americans.Semantic proximity Read ↗

HLA phenotype is a factor in determining rate of disease progression and outcome in HIV-1-infected individuals.Semantic proximity Read ↗

AIDS restriction HLA allotypes target distinct intervals of HIV-1 pathogenesis.Semantic proximity Read ↗

The association of human leukocyte antigen alleles with clinical disease progression in HIV-positive cohorts with varied treatment strategies.Semantic proximity Read ↗

The influence of HLA genotype on AIDS.Semantic proximity Read ↗

HIV and HLA class I: an evolving relationship.Semantic proximity Read ↗

HIV-1 diversity versus HLA class I polymorphism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.