Article
The influence of HLA genotype on AIDS.
Annual review of medicine - 1 Jan 2003
Carrington Mary, O'Brien Stephen J
Abstract excerpt
Genetic resistance to infectious diseases is likely to involve a complex array of immune-response and other genes with variants that impose subtle but significant consequences on gene expression or protein function. We have gained considerable insight into the genetic determinants of HIV-1 disease, and the HLA class I genes appear to be highly influential in this regard. Numerous reports have identified a role...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.