HLA phenotype is a factor in determining rate of disease progression and outcome in HIV-1-infected individuals.

doi:10.1089/aid.1992.8.1345

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Article

HLA phenotype is a factor in determining rate of disease progression and outcome in HIV-1-infected individuals.

AIDS research and human retroviruses - 1 Aug 1992

Mann D L, Carrington M, O'Donnell M, Miller T, Goedert J

Abstract excerpt

HLA allele frequencies were examined for possible association(s) with the rate of disease progression and with the disease outcome (AIDS diagnosis) in a population of HIV-1-infected individuals. Certain alleles were associated with the relative rate of CD4+ T-cell decline. Association of particul...

Topics

Alleles
CD4-Positive T-Lymphocytes
Disease Susceptibility
Genetic Predisposition to Disease
HIV Infections
HIV-1
HLA Antigens
Humans
Leukocyte Count
Male
Phenotype

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