Article
HLA phenotype is a factor in determining rate of disease progression and outcome in HIV-1-infected individuals.
AIDS research and human retroviruses - 1 Aug 1992
Mann D L, Carrington M, O'Donnell M, Miller T, Goedert J
Abstract excerpt
HLA allele frequencies were examined for possible association(s) with the rate of disease progression and with the disease outcome (AIDS diagnosis) in a population of HIV-1-infected individuals. Certain alleles were associated with the relative rate of CD4+ T-cell decline. Association of particular alleles with several disease outcomes associated with infection was also observed. It is important to keep these two...
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